SOFIVA Hereditary Cancer

24 types of hereditary cancer related genetic tests

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■Cancer and gene

Cancer begins when genes in a cell become abnormal and the cell
starts to grow and divide out of control.Drugs have been developed that target some of the gene changes in certain cancers which called targeted therapy. They are a cornerstone of precision medicine, a form of
medicine that uses information about a person's genes to prevent and
treat cancer.

■ What is hereditary cancer?

Everyone has two copies of most genes, one copy from mother and one from father. Most people are born with two normal copies of each gene. Hereditary cancers occur when a person is born with mutations in one
copy of gene. In this case, the changes were inherited from the mother or father.

People with an inherited gene change have a 50% chance to pass down the genetic mutation to children. Not all people who inherit a mutation
in one or more of their genes will develop cancer, however, the risk for
developing cancer will be greater if a person inherits a mutation in a
cancer-related gene.

■ Hereditary vs. Sporadic cancer

Hereditary cancers are different from sporadic cancers in ways that
could effect treatment choices:

◆ Hereditary cancer often occur earlier than the sporadic form of the
same cancer, so experts often recommend different screening, at a
younger age for people with hereditary cancer in their family.

◆ Individuals who have inherited a gene mutation may be at a higher risk for more than one type of cancer. This may affect cancer treatment
options or follow-up care.


◆ who have cancer in their family

◆ who would like to know the risk of cancer


◆ 24 types of hereditary cancer:

Meningeal cancer, Multiple endocrine neoplasia, Esophageal cancer,
Pancreatic cancer, Parathyroid cancer, Skin cancer, Soft tissue cancer, Stomach cancer, Thyroid cancer, Urethral cancer, Adrenal cancer,
Autonomic ganglion cancer, Breast cancer, Central nervous system
cancer, Gastrointestinal cancer, Kidney cancer, Colorectal cancer, Liver cancer, Lung cancer, Leukemia, Testicular cancer, Prostate cancer,
Ovarian cancer, Endometrial cancer

◆ Genes analyzed:52 genes

◆ Technology:NGS

Patient Story

How It Works

Step1. Consulting with physician to understand the test content

Step2. Go hospitals to collect specimen and fill out the consent form

Step3. Send specimen to SOFIVA lab

Step4. DNA extraction and analysis

Step5. The report will be provided in 4 weeks